Its HUMAN HEPATITIS B VIRUS
This is the virus we got from sequencing the gene sample given by Mr. Cheong..
So...
We are going to First be Introduced to this very InTeResTing virus.. Keke
What Exactly Is This virus??
Biological Characteristic of Hepatitis B Virus (HBV)
Hepatitis B virus is a member of the family Hepadnaviridae, which includes woodchuck hepatitis virus, duck hepatits virus, and ground squirrel hepatitis virus.
A notable feature of the virus is its efficient use of genetic information to encode four groups of proteins and their regulatory elements. This is achieved by shifting the reading frames over the same genetic material in order to encode distinct proteins within the same regions.
The 4 proteins encoded by HBV genome are the envelope, the nucleocapsid, the “X”, and a DNA polymerase.
HBV integrate DNA into host cells and they are oncogenic. HBV genome encodes 3 envelope proteins: pre-S1, pre-S2, and HBsAg is a glycosylated lipoprotein that contain the major site for binding of neutralizing antibody, designated the a determinant.
4 subtype epitopes have been identified: adw, ayw, adr, and ayr. Human appear to be the only natural host for HBV. HBV can produce a chronic infection, but the characteristics and determinants of virus persistence are not clearly defined except on an epidemiologic basis. Age at infection is the most important factor for determining the risk of chronic HBV infection.
The risk of chronic HBV infection for:
Newborns = 90%
Children below 5 years old = 30%
Older children, adolescents and adults = 2 – 10%
Male sex, Down’s syndrome or depressed cell-mediated immunity from drugs or infection =
Feeling a little afraid and worried? ;p Now lets see how can you actually get INFECTED
Resevoir and transmission
It seems that the only known reservoir for Hepatitis B Virus (HBV) is human.
This virus is transmitted through broken skin (cuts) and/or mucosal contact with infectious blood or body fluids (e.g., blood, semen). The possible modes of transmission from an infected person are:
Sexual intercourse
Sharing of needles, syringes, or drug-preparation equipment
Blood contact through birth
Contact with blood or wounds
Sharing of personal and sharp objects such as razors or toothbrushes
My dear Frens, hope u all are willing to post some comments to us. Hope u like our blog style..Thanks Veli de Much..
ReplyDeleteThe video above are the type of Hepatitis B Virus found in Human body.. Nice looking but so jahat can cause ppl die..haha
ReplyDeletei thought it also can transmit by the sea food?? the si ham....???
ReplyDeleteor is another hepatitis a?
To answer magi question: Nope,hepatitis B virus wil only stay in human blood.it's not type parasite,bt it's a virus.so during unsafe sex,it can also transmit through body fluid Eg:Sperms n semen.So de way Hep B virus transmit is all in human body,not related with food.Share needle oso can transmit,cos got blood.Thanks (",)
ReplyDeleteThanks for correcting the public perception about mode of transmission for HepB virus...
ReplyDelete"HBV integrate DNA into host cells and they are oncogenic. HBV genome encodes 3 envelope proteins: pre-S1, pre-S2, and HBsAg is a glycosylated lipoprotein that contain the major site for binding of neutralizing antibody, designated the a determinant"... This part is not clear...can explain a bit more?
thanks....
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ReplyDelete